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STX1A 抗体 (N-Term)

STX1A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792295
发货至: 中国
  • 抗原 See all STX1A 抗体
    STX1A (Syntaxin 1A (Brain) (STX1A))
    抗原表位
    • 16
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    • 8
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    • 2
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    N-Term
    适用
    • 72
    • 44
    • 28
    • 9
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    • 5
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    • 2
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    人, 小鼠, 大鼠, Cow, 犬, 豚鼠
    宿主
    • 78
    • 8
    • 2
    • 1
    克隆类型
    • 80
    • 9
    多克隆
    标记
    • 48
    • 7
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    • 2
    • 2
    • 2
    • 2
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    • 1
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    This STX1A antibody is un-conjugated
    应用范围
    • 52
    • 38
    • 29
    • 16
    • 16
    • 14
    • 13
    • 13
    • 8
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    KDRTQELRTA KDSDDDDDVA VTVDRDRFMD EFFEQVEEIR GFIDKIAENV
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against STX1A. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human STX1A
    Top Product
    Discover our top product STX1A Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 288 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    STX1A (Syntaxin 1A (Brain) (STX1A))
    别名
    STX1A (STX1A 产品)
    别名
    HPC-1 antibody, P35-1 antibody, STX1 antibody, SYN1A antibody, STX1A antibody, hpc-1 antibody, p35-1 antibody, stx1 antibody, sx1a antibody, syntaxin1a antibody, CG10716 antibody, CG18615 antibody, CG31136 antibody, CG5448 antibody, CT30033 antibody, Dm Syx1 antibody, DmSyx1A antibody, Dmel\\CG31136 antibody, SYX1A antibody, Syt1A antibody, Syx antibody, Syx-1A antibody, Syx1 antibody, Syx1a antibody, SyxA antibody, anon-EST:Gibbs4 antibody, anon-WO02059370.54 antibody, dSyx1 antibody, l(3)06737 antibody, synt antibody, syt-1A antibody, syx antibody, syx-1 antibody, syx-1A antibody, syx1 antibody, syx1A antibody, syntaxin 1A antibody, syntaxin 1A (brain) antibody, Syntaxin 1A antibody, syntaxin-1A antibody, STX1A antibody, Stx1a antibody, stx1a antibody, Syx1A antibody, EDI_005240 antibody, Tsp_07354 antibody
    背景
    Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor which produces explosive exocytosis. Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1253 BC064644.1 1-1253 1254-2117 BC000444.2 1209-2072
    Alias Symbols: HPC-1, STX1, p35-1, P35-1, SYN1A
    Protein Interaction Partner: STXBP1, SUMO1P1, TXLNA, TXLNB, NAPB, VAMP5, SNAP29, VAPB, SNAP23, STX1A, PSMA3, KCNB1, Htt, SNAP25, SLC6A3, SLC6A2, PPP1CA, pnut, Sep1, SNPH, TRDMT1, CCSER2, VPS11, SYT7, VPS18, RIMS1, CPLX1, SLC6A5, STXBP5, SYTL4, STXBP6, UNC13B, STX8, RAB27A, NAPA, VAMP
    Protein Size: 288
    分子量
    33 kDa
    基因ID
    6804
    NCBI登录号
    NM_004603, NP_004594
    UniProt
    Q16623
    途径
    Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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