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BCL2A1 抗体 (C-Term)

This anti-BCL2A1 antibody is a 兔 多克隆 antibody detecting BCL2A1 in WB. Suitable for 大鼠, Pig 和 犬.
产品编号 ABIN2792231
发货至: 中国

Quick Overview for BCL2A1 抗体 (C-Term) (ABIN2792231)

抗原

See all BCL2A1 抗体
BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

适用

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大鼠, Pig, 犬

宿主

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克隆类型

  • 35
  • 11
多克隆

标记

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This BCL2A1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    FIMNNTGEWI RQNGGWENGF VKKFEPKSGW MTFLEVTGKI CEMLSLLKQY

    预测反应

    Dog: 90%, Pig: 85%, Rat: 78%

    产品特性

    This is a rabbit polyclonal antibody against BCL2A1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human BCL2A1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 175 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

    别名

    BCL2A1

    背景

    BCL2A1s a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
    Alias Symbols: GRS, BFL1, ACC-1, ACC-2, HBPA1, BCL2L5
    Protein Interaction Partner: FAM9B, NR4A1, BIK, BAK1, APP, HAT1, BBC3, PMAIP1, BOK, BCL2L11, HRK, BAD, BID, BAX, GRB2, BMF,
    Protein Size: 175

    分子量

    20 kDa

    基因ID

    597

    NCBI登录号

    NM_004049, NP_004040

    UniProt

    Q16548
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