BCL2A1 抗体 (C-Term)
Quick Overview for BCL2A1 抗体 (C-Term) (ABIN2792231)
抗原
See all BCL2A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FIMNNTGEWI RQNGGWENGF VKKFEPKSGW MTFLEVTGKI CEMLSLLKQY
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预测反应
- Dog: 90%, Pig: 85%, Rat: 78%
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产品特性
- This is a rabbit polyclonal antibody against BCL2A1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human BCL2A1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 175 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
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别名
- BCL2A1
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背景
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BCL2A1s a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
Alias Symbols: GRS, BFL1, ACC-1, ACC-2, HBPA1, BCL2L5
Protein Interaction Partner: FAM9B, NR4A1, BIK, BAK1, APP, HAT1, BBC3, PMAIP1, BOK, BCL2L11, HRK, BAD, BID, BAX, GRB2, BMF,
Protein Size: 175 -
分子量
- 20 kDa
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基因ID
- 597
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NCBI登录号
- NM_004049, NP_004040
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UniProt
- Q16548
抗原
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