PDCD4 抗体 (N-Term)
Quick Overview for PDCD4 抗体 (N-Term) (ABIN2792230)
抗原
See all PDCD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MTKYPDNLSD SLFSGDEENA GTEEIKNEIN GNWISASSIN EARINAKAKR
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PDCD4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PDCD4
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 458 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells." in: Molecular human reproduction, Vol. 16, Issue 3, pp. 215-27, (2010) (PubMed).
: "miR-21: an oncomir on strike in prostate cancer." in: Molecular cancer, Vol. 9, pp. 12, (2010) (PubMed).
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: "microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells." in: Molecular human reproduction, Vol. 16, Issue 3, pp. 215-27, (2010) (PubMed).
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- PDCD4 (Programmed Cell Death 4 (PDCD4))
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别名
- PDCD4
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背景
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PDCD4 is a protein localized to the nucleus in proliferating cells. Expression of its gene is modulated by cytokines in natural killer and T cells. PDCD4 is thought to play a role in apoptosis but the specific role has not yet been determined.This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.
Alias Symbols: H731, MGC33046, MGC33047
Protein Interaction Partner: EIF4A2, FBXW11, EIF4A3, PAIP1, ARPC1B, UFD1L, TPD52, BTF3, AAMP, IGSF8, CD81, DAXX, UBC, CSNK2A1, VCP, NR1H2, PSEN2, PSEN1, NAP1L1, APOE, BTRC, RPS6KA1, EIF4A1, ELAVL1, SUMO2, EMD, PDCD4, EIF4G1, RPL5, RPLP1, RPS13,
Protein Size: 458 -
分子量
- 50 kDa
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基因ID
- 27250
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NCBI登录号
- NM_145341, NP_663314
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UniProt
- Q53EL6
抗原
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