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Caveolin 3 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects Caveolin 3 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, Pig 和 Cow.
产品编号 ABIN2792221
发货至: 中国
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Quick Overview for Caveolin 3 抗体 (N-Term) (ABIN2792221)

抗原

See all Caveolin 3 (CAV3) 抗体
Caveolin 3 (CAV3)

适用

  • 58
  • 24
  • 23
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Pig, Cow

宿主

  • 51
  • 8
  • 1

克隆类型

  • 37
  • 23
多克隆

标记

  • 24
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
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  • 1
This Caveolin 3 antibody is un-conjugated

应用范围

  • 40
  • 19
  • 15
  • 10
  • 6
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 13
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    MMAEEHTDLE AQIVKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPVG

    预测反应

    Cow: 100%, Human: 100%, Mouse: 84%, Pig: 92%, Rat: 84%

    产品特性

    This is a rabbit polyclonal antibody against CAV3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CAV3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 151 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Caveolin 3 (CAV3)

    别名

    CAV3

    背景

    CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
    Alias Symbols: LQT9, VIP21, LGMD1C, VIP-21
    Protein Interaction Partner: KCNMA1, PTGES3, SCN5A, PCBP1, NEDD4L, KCNH2, SUMO2, SUMO3, ADRB2, JPH2, SLC22A11, DYSF, PFKM, SLC8A1, NOS1, INSR, GNAS, EGFR, DAG1, PDGFRB, PDGFRA,
    Protein Size: 151

    分子量

    17 kDa

    基因ID

    859

    NCBI登录号

    NM_001234, NP_001225

    UniProt

    P56539

    途径

    Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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