Caveolin 3 抗体 (N-Term)
Quick Overview for Caveolin 3 抗体 (N-Term) (ABIN2792221)
抗原
See all Caveolin 3 (CAV3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MMAEEHTDLE AQIVKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPVG
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预测反应
- Cow: 100%, Human: 100%, Mouse: 84%, Pig: 92%, Rat: 84%
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产品特性
- This is a rabbit polyclonal antibody against CAV3. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CAV3
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 151 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Caveolin 3 (CAV3)
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别名
- CAV3
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背景
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CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Alias Symbols: LQT9, VIP21, LGMD1C, VIP-21
Protein Interaction Partner: KCNMA1, PTGES3, SCN5A, PCBP1, NEDD4L, KCNH2, SUMO2, SUMO3, ADRB2, JPH2, SLC22A11, DYSF, PFKM, SLC8A1, NOS1, INSR, GNAS, EGFR, DAG1, PDGFRB, PDGFRA,
Protein Size: 151 -
分子量
- 17 kDa
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基因ID
- 859
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NCBI登录号
- NM_001234, NP_001225
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UniProt
- P56539
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途径
- Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
抗原
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