TRAF4 抗体 (Middle Region)
Quick Overview for TRAF4 抗体 (Middle Region) (ABIN2792211)
抗原
See all TRAF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- LEAPGGWLDH SNTSLGINTP VNGSPVCLEA WDPASAGPAR FSLSLLLFFL
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against TRAF4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TRAF4
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 470 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))
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别名
- TRAF4
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背景
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TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CART1, MLN62, RNF83
Protein Interaction Partner: HOMEZ, BYSL, REXO1L6P, PKD1P1, KANSL1, BCL6B, UBL4B, KRT40, FBXL18, BANP, SPDL1, ALKBH4, WBP11, ZNF581, ISYNA1, TBC1D7, GORASP2, EXOC7, BAHD1, WWP2, WWP1, MRPL28, NOS1AP, TRAF4, UBL4A, ZNF3, SUMO1, UBC, TYK2, TP53BP2, QARS, KRT31, ARNT2, TRAF2, USP15, TGF
Protein Size: 470 -
分子量
- 53 kDa
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基因ID
- 9618
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NCBI登录号
- NM_004295, NP_004286
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UniProt
- Q9BUZ4
抗原
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