CXCR6 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for CXCR6 抗体 (N-Term) (ABIN487291)
抗原
See all CXCR6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- AEHDYHEDYG FSSFNDSSQE EHQDFLQFSK VFLPCMYLVV FVCGLVGNSL
-
预测反应
- Human: 100%
-
产品特性
- This is a rabbit polyclonal antibody against CXCR6. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CXCR6
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 342 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
-
别名
- CXCR6
-
背景
-
CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung.
Alias Symbols: BONZO, CD186, STRL33, TYMSTR
Protein Interaction Partner: CXCL16,
Protein Size: 342 -
分子量
- 39 kDa
-
基因ID
- 10663
-
NCBI登录号
- NM_006564, NP_006555
-
UniProt
- O00574
抗原
-