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RBX1 抗体 (Middle Region)

Cited in 1 publication. This 兔 多克隆 anti-RBX1 antibody specifically detects RBX1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼 和 豚鼠 samples.
产品编号 ABIN2792171
发货至: 中国
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Quick Overview for RBX1 抗体 (Middle Region) (ABIN2792171)

抗原

See all RBX1 抗体
RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))

适用

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人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This RBX1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    NQASATSEEC TVAWGVCNHA FHFHCISRWL KTRQVCPLDN REWEFQKYGH

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against RBX1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human RBX1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 108 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Maerki, Olma, Staubli, Steigemann, Gerlich, Quadroni, Sumara, Peter: "The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 791-800, (2009) (PubMed).

  • 抗原

    RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))

    别名

    RBX1

    背景

    ROC1 encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization. It also may be involved in the regulation of protein turn-over.
    Alias Symbols: ROC1, RNF75, BA554C12.1
    Protein Interaction Partner: CDT1, CDC34, KEAP1, UBE2L6, UBE2M, CUL1, CUL3, CUL4B, UBE2D3, UBE2D2, UBE2D1, DAB2IP, UBC, TP53, PRAME, DCUN1D1, CUL2, DCUN1D3, MAP4K1, VHL, NEDD4, MTSS1, VRK2, HIST1H4A, GFPT1, CTNNB1, CCNE1, DCUN1D5, FBXL5, RHOBTB3, SAMHD1, UBC12, FBXL15, UBE2R2, SERTAD
    Protein Size: 108

    分子量

    12 kDa

    基因ID

    9978

    NCBI登录号

    NM_014248, NP_055063

    UniProt

    P62877

    途径

    Cell Division Cycle, M Phase, SARS-CoV-2 Protein Interactome
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