CDC25C 抗体 (N-Term)
Quick Overview for CDC25C 抗体 (N-Term) (ABIN2792164)
抗原
See all CDC25C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- QKYEKLEKIG EGTYGTVFKA KNRETHEIVA LKRVRLDDDD EGVPSSALRE
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预测反应
- Human: 100%, Mouse: 91%, Rabbit: 83%
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产品特性
- This is a rabbit polyclonal antibody against CDC25C. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CDC25C
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 400 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
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别名
- CDC25C
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背景
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CDC25C gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Alias Symbols: CDC25, PPP1R60
Protein Interaction Partner: CDC37, UBC, HSP90AA1, HSPA4, YWHAB, YWHAQ, YWHAZ, YWHAH, YWHAG, YWHAE, PKN1, SFN, MAPK9, PLK1, CHEK1, CHEK2, CDS1, MARK3, BRSK2, CDK2, PCNA, Cdk1, USP17L2, MAPK3, MAPK1, BRSK1, LZTS1, PLK3, NEDD4, PIN1, MAPK14, TP53, HRAS, LCK, CCNB1, CCNA2, SRC, SP1,
Protein Size: 400 -
分子量
- 45 kDa
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基因ID
- 995
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NCBI登录号
- NM_022809, NP_073720
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UniProt
- P30307
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途径
- Cell Division Cycle, M Phase
抗原
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