Cyclin H 抗体 (C-Term)
Quick Overview for Cyclin H 抗体 (C-Term) (ABIN2792161)
抗原
See all Cyclin H (CCNH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- KQKLERCHSA ELALNVITKK RKGYEDDDYV SKKSKHEEEE WTDDDLVESL
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预测反应
- Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 83%, Rabbit: 83%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against CCNH. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CCNH
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anti-Cyclin H (CCNH) (AA 1-110) antibody
CCNH 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-Cyclin H (CCNH) (AA 1-323) antibodyCCNH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 1-323) antibodyCCNH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin H (CCNH) (pThr315) antibodyCCNH 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 221-323) antibodyCCNH 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 261-319) antibodyCCNH 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) antibodyCCNH 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Cyclin H (CCNH) (C-Term) antibodyCCNH 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) (C-Term) antibodyCCNH 适用: 人, 小鼠, 大鼠, Pig, 豚鼠, 兔, 猴, 马, Cow, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 269-299), (C-Term) antibodyCCNH 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14888 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 323 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Cyclin H (CCNH)
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别名
- CCNH
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背景
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Cyclin H regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. It is involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Alias Symbols: CAK, p34, p37
Protein Interaction Partner: SFN, GOLGA2, SSX2IP, CCDC170, CCDC33, DUSP12, SSSCA1, NDC80, CALCOCO2, PPFIA1, PSMA1, KLC3, RPA3, RPA2, RPA1, NEDD4, CDK7, CDK8, CDK2, CCNC, MNAT1, MBP, CTD, CDK20, CTBP2, CSNK2B, TRIM8, GANAB, RARB, POLR2A, GTF2H4, ERCC2, tat, POLR2B, CDK9, BRCA1, GTF2H1
Protein Size: 323 -
分子量
- 38 kDa
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基因ID
- 902
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NCBI登录号
- NM_001239, NP_001230
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UniProt
- P51946
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
抗原
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