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CDK1 抗体 (C-Term)

This anti-CDK1 antibody is a 兔 多克隆 antibody detecting CDK1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN2792159
发货至: 中国

Quick Overview for CDK1 抗体 (C-Term) (ABIN2792159)

抗原

See all CDK1 抗体
CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    SLASHVKNLD ENGLDLLSKM LIYDPAKRIS GKMALNHPYF NDLDNQIKKM

    产品特性

    This is a rabbit polyclonal antibody against CDC2. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CDC2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 297 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

    别名

    CDC2

    背景

    The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
    Alias Symbols: CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2
    Protein Interaction Partner: ABL1, SIRT1, CDC37, HUWE1, BTRC, UBC, HSP90AA1, HSPA4, HIST1H1A, GADD45A, CKS1B, USP16, Samhd1, UIMC1, SUMO2, CCNA2, STAU1, RNF2, CKS2, ZRANB2, CDKN1B, CDKN1A, CDK1, CCNB1, FBXO6, CCNB2, PKMYT1, SQSTM1, EGFR, PTMA, DCTN6, RGCC, BAG3, CDC25B, BCL2, TP53BP1
    Protein Size: 297

    分子量

    34 kDa

    基因ID

    983

    NCBI登录号

    NM_001786, NP_001777

    UniProt

    P06493

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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