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14-3-3 eta 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-14-3-3 eta antibody is suitable to detect 14-3-3 eta in samples from 人, 兔, 犬 和 斑马鱼. It has been validated for WB 和 IHC.
产品编号 ABIN2792143
发货至: 中国
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Quick Overview for 14-3-3 eta 抗体 (N-Term) (ABIN2792143)

抗原

See all 14-3-3 eta (YWHAH) 抗体
14-3-3 eta (YWHAH)

适用

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人, 兔, 犬, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This 14-3-3 eta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    ADGNEKKLEK VKAYREKIEK ELETVCNDVL SLLDKFLIKN CNDFQYESKV

    预测反应

    Dog: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 78%

    产品特性

    This is a rabbit polyclonal antibody against YWHAH. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAH
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 246 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ubl, Berg, Holzmann, Krüger, Berger, Arzberger, Bornemann, Riess: "14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta." in: Brain research. Molecular brain research, Vol. 108, Issue 1-2, pp. 33-9, (2002) (PubMed).

  • 抗原

    14-3-3 eta (YWHAH)

    别名

    YWHAH

    背景

    The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: YWHA1
    Protein Interaction Partner: DTL, HUWE1, ABL1, SIK3, SUMO2, IRS4, CBL, UBC, UBFD1, EIF5, TBCB, CAPNS1, ALDH7A1, UBE2R2, ISOC1, FERMT2, YWHAQ, PDIA4, YWHAZ, YWHAG, YWHAE, XPO1, VCL, SNRPD2, PCYT2, PTMA, PAK2, PAFAH1B1, MYO1E, HNRNPK, HMGB3, GSS, GNAI3, G6PD, PPP1CA, MARK3, LRRK2, SAV1
    Protein Size: 246

    分子量

    28 kDa

    基因ID

    7533

    NCBI登录号

    NM_003405, NP_003396

    UniProt

    Q04917

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction
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