14-3-3 eta 抗体 (N-Term)
Quick Overview for 14-3-3 eta 抗体 (N-Term) (ABIN2792143)
抗原
See all 14-3-3 eta (YWHAH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ADGNEKKLEK VKAYREKIEK ELETVCNDVL SLLDKFLIKN CNDFQYESKV
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预测反应
- Dog: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 78%
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产品特性
- This is a rabbit polyclonal antibody against YWHAH. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAH
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 246 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta." in: Brain research. Molecular brain research, Vol. 108, Issue 1-2, pp. 33-9, (2002) (PubMed).
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: "14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta." in: Brain research. Molecular brain research, Vol. 108, Issue 1-2, pp. 33-9, (2002) (PubMed).
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- 14-3-3 eta (YWHAH)
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别名
- YWHAH
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背景
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The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: YWHA1
Protein Interaction Partner: DTL, HUWE1, ABL1, SIK3, SUMO2, IRS4, CBL, UBC, UBFD1, EIF5, TBCB, CAPNS1, ALDH7A1, UBE2R2, ISOC1, FERMT2, YWHAQ, PDIA4, YWHAZ, YWHAG, YWHAE, XPO1, VCL, SNRPD2, PCYT2, PTMA, PAK2, PAFAH1B1, MYO1E, HNRNPK, HMGB3, GSS, GNAI3, G6PD, PPP1CA, MARK3, LRRK2, SAV1
Protein Size: 246 -
分子量
- 28 kDa
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基因ID
- 7533
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NCBI登录号
- NM_003405, NP_003396
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UniProt
- Q04917
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction
抗原
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