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YWHAE 抗体 (Middle Region)

This anti-YWHAE antibody is a 兔 多克隆 antibody detecting YWHAE in WB. Suitable for 小鼠, 斑马鱼, 豚鼠 和 犬. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2792142
发货至: 中国

Quick Overview for YWHAE 抗体 (Middle Region) (ABIN2792142)

抗原

See all YWHAE 抗体
YWHAE (14-3-3 epsilon (YWHAE))

适用

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小鼠, 斑马鱼, 豚鼠, 犬

宿主

  • 59
  • 15
  • 1

克隆类型

  • 51
  • 24
多克隆

标记

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This YWHAE antibody is un-conjugated

应用范围

  • 58
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Western Blotting (WB)
  • 抗原表位

    • 15
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    • 9
    • 1
    • 1
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    • 1
    • 1
    • 1
    Middle Region

    序列

    ELDTLSEESY KDSTLIMQLL RDNLTLWTSD MQGDGEEQNK EALQDVEDEN

    预测反应

    Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against YWHAE. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human YWHAE
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 255 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tak, Jang, Kim, Park, Suk, Yoon, Ahn, Lee, Joe: "14-3-3epsilon inhibits MK5-mediated cell migration by disrupting F-actin polymerization." in: Cellular signalling, Vol. 19, Issue 11, pp. 2379-87, (2007) (PubMed).

  • 抗原

    YWHAE (14-3-3 epsilon (YWHAE))

    别名

    YWHAE

    背景

    YWHAE is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAE binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. The binding generally results in the modulation of the activity of the binding partner.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: 14-3-3E, FLJ45465, KCIP-1, MDCR, MDS
    Protein Interaction Partner: DTL, HUWE1, FAM53C, FBXW11, SORBS2, UBC, ABL1, GRB10, SIK2, CEP57, SIK3, TP53, IRS4, CBL, TUBB2A, TWF2, PROSC, FERMT2, PDIA4, RAP1GDS1, PTMA, PPP1R2, PDHB, PAK2, PAFAH1B2, YWHAH, XPO1, VCL, GSS, G6PD, EIF5, TBCB, CAPNS1, CAPN2, ALDH7A1, ATIC, ASNS, SCPEP1
    Protein Size: 255

    分子量

    29 kDa

    基因ID

    7531

    NCBI登录号

    NM_006761, NP_006752

    UniProt

    P62258

    途径

    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
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