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RIPK2 抗体 (Middle Region)

The 兔 多克隆 anti-RIPK2 antibody is suitable to detect RIPK2 in samples from 人, 小鼠, 大鼠, Cow, 犬, 马, 兔 和 豚鼠. It has been validated for WB 和 IF.
产品编号 ABIN2792136
发货至: 中国
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Quick Overview for RIPK2 抗体 (Middle Region) (ABIN2792136)

抗原

See all RIPK2 抗体
RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠

宿主

  • 58
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克隆类型

  • 59
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多克隆

标记

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This RIPK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    Middle Region

    序列

    LRQERKRPLL DLHIELNGYM YDWNSRVSAK EKYYVWLQHT LRKKLILSYT

    预测反应

    Cow: 85%, Dog: 85%, Guinea Pig: 78%, Horse: 85%, Human: 85%, Mouse: 78%, Rabbit: 84%, Rat: 78%

    产品特性

    This is a rabbit polyclonal antibody against RIPK2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human RIPK2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 540 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

    别名

    RIPK2

    背景

    RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
    Protein Interaction Partner: RIPK2, XIAP, UBC, TRAF3, KDM3A, PRMT2, PELI3, NOD1, MAP3K7, CHUK, LRRK2, NOD2, TRAF4, TRAF6, MAP3K4, CASP12, NAT16, RNF31, RIPK1, MAVS, TRAF2, TAB2, TAB1, IKBKG, BIRC3, BIRC2, CARD16, CARD6, UBE2I, SMURF1, CFLAR, BCL10, TLR4, TLR2, TRAF5, CASP8, TRAF1, SM
    Protein Size: 540

    分子量

    61 kDa

    基因ID

    8767

    NCBI登录号

    NM_003821, NP_003812

    UniProt

    O43353

    途径

    TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
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