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FOXO4 抗体 (Middle Region)

FOXO4 适用: 人, 小鼠, 大鼠, Pig, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792112
发货至: 中国
  • 抗原 See all FOXO4 抗体
    FOXO4 (Forkhead Box O4 (FOXO4))
    抗原表位
    • 20
    • 18
    • 16
    • 10
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 139
    • 71
    • 63
    • 10
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠, Pig, 犬, 马
    宿主
    • 137
    • 1
    • 1
    克隆类型
    • 126
    • 13
    多克隆
    标记
    • 67
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    This FOXO4 antibody is un-conjugated
    应用范围
    • 107
    • 50
    • 39
    • 39
    • 25
    • 18
    • 17
    • 9
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    YLYQILQGIV FCHSRRVLHR DLKPQNLLID DKGTIKLADF GLARAFGIPI
    预测反应
    Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against FOXO4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human FOXO4
    Top Product
    Discover our top product FOXO4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 505 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FOXO4 (Forkhead Box O4 (FOXO4))
    别名
    FOXO4 (FOXO4 产品)
    别名
    FOXO4 antibody, foxo4 antibody, AFX antibody, AFX1 antibody, MLLT7 antibody, Afxh antibody, Mllt7 antibody, afx antibody, RGD1561201 antibody, forkhead box O4 antibody, forkhead box O4 L homeolog antibody, FOXO4 antibody, foxo4.L antibody, Foxo4 antibody
    背景
    FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
    Alias Symbols: AFX, AFX1, MGC120490, MLLT7
    Protein Interaction Partner: REL, SFN, AKT1, OGT, UBC, ATXN3, MDM2, NLK, USP7, CTNNB1, CREBBP, VDR, SIRT1, SMAD3, XPO1, YWHAZ, SMAD4, FOXG1, AKT2, ESR1, PIN1, CCND1, CDKN1A,
    Protein Size: 505
    分子量
    54 kDa
    基因ID
    4303
    NCBI登录号
    NM_005938, NP_005929
    UniProt
    P98177
    途径
    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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