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FOXO4 抗体 (Middle Region)

This 兔 多克隆 anti-FOXO4 antibody specifically detects FOXO4 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Pig, 犬 和 马 samples.
产品编号 ABIN2792112
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FOXO4 抗体 (Middle Region) (ABIN2792112)

抗原

See all FOXO4 抗体
FOXO4 (Forkhead Box O4 (FOXO4))

适用

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人, 小鼠, 大鼠, Pig, 犬, 马

宿主

  • 155
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克隆类型

  • 124
  • 33
多克隆

标记

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This FOXO4 antibody is un-conjugated

应用范围

  • 127
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  • 9
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Western Blotting (WB)
  • 抗原表位

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    • 15
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    Middle Region

    序列

    YLYQILQGIV FCHSRRVLHR DLKPQNLLID DKGTIKLADF GLARAFGIPI

    预测反应

    Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against FOXO4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human FOXO4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 505 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    FOXO4 (Forkhead Box O4 (FOXO4))

    别名

    FOXO4

    背景

    FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
    Alias Symbols: AFX, AFX1, MGC120490, MLLT7
    Protein Interaction Partner: REL, SFN, AKT1, OGT, UBC, ATXN3, MDM2, NLK, USP7, CTNNB1, CREBBP, VDR, SIRT1, SMAD3, XPO1, YWHAZ, SMAD4, FOXG1, AKT2, ESR1, PIN1, CCND1, CDKN1A,
    Protein Size: 505

    分子量

    54 kDa

    基因ID

    4303

    NCBI登录号

    NM_005938, NP_005929

    UniProt

    P98177

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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