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SIRPA 抗体 (C-Term)

Name: SIRPA 抗体 (C-Term)
SKU: ABIN2792091
Availability: OutOfStock

SIRPA 适用: 人, 小鼠, 大鼠, Cow, Pig, 马 WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-SIRPA Antibody Titration: 0. (SIRPA 抗体 (C-Term))

1 image

产品编号 ABIN2792091

发货至: 中国

Datasheet as PDF

抗原 See all SIRPA 抗体

SIRPA (Signal-Regulatory Protein alpha (SIRPA))
抗原表位
16

11

5

2

2

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
71

38

32

9

7

4

3

2
人, 小鼠, 大鼠, Cow, Pig, 马
宿主
58

32

1
兔
Compatible Secondaries
克隆类型
55

36
多克隆
标记
45

11

6

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This SIRPA antibody is un-conjugated
应用范围
56

46

19

19

13

13

11

10

9

1

1

1

1
Western Blotting (WB)

序列

QTSPQPASED TLTYADLDMV HLNRTPKQPA PKPEPSFSEY ASVQVPRK

预测反应

Cow: 92%, Horse: 84%, Human: 100%, Mouse: 100%, Pig: 90%, Rat: 90%

产品特性

This is a rabbit polyclonal antibody against SIRPA. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human SIRPA

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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 28-507) antibody
SIRPA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C7 unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 235-373) antibody
SIRPA 适用: 人 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 2H7E2 unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-370) antibody
SIRPA 适用: 人 FACS, ELISA, IP, IF 宿主: 兔 Monoclonal DM8 unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 395-504) antibody
SIRPA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 56-296) antibody
SIRPA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (C-Term) antibody
SIRPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) antibody
SIRPA 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 151-250) antibody
SIRPA 适用: 人, 小鼠 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 105-324) antibody
SIRPA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-373) antibody
SIRPA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 504 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

SIRPA (Signal-Regulatory Protein alpha (SIRPA))

别名

SIRPA (SIRPA 产品)

别名

BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody

背景

SIRPA is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.
Alias Symbols: BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2
Protein Interaction Partner: CCDC57, KRT40, TRIM2, TRIM27, KRT31, KRT15, UBC, GRB2, Htt, NOL3, IL1RAP, CD47, PTPN6, PTPN11, JAK2,
Protein Size: 504

分子量

52 kDa

基因ID

140885

NCBI登录号

NM_080792, NP_542970

UniProt

B2R6C3