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beta 2 Adrenergic Receptor 抗体 (Middle Region)

ADRB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792089
发货至: 中国
  • 抗原 See all beta 2 Adrenergic Receptor (ADRB2) 抗体
    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
    抗原表位
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    Middle Region
    适用
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    宿主
    • 149
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    克隆类型
    • 137
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    多克隆
    标记
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    This beta 2 Adrenergic Receptor antibody is un-conjugated
    应用范围
    • 111
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    Western Blotting (WB)
    序列
    TGEQSGYHVE QEKENKLLCE DLPGTEDFVG HQGTVPSDNI DSQGRNCSTN
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against ADRB2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human ADRB2
    Top Product
    Discover our top product ADRB2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 413 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Penco, Buscema, Patrosso, Marocchi, Grossi: "New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background." in: BMC bioinformatics, Vol. 9, pp. 254, (2008) (PubMed).

  • 抗原
    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
    别名
    ADRB2 (ADRB2 产品)
    别名
    zgc:162188 antibody, adrb2 antibody, Adrb-2 antibody, Badm antibody, Gpcr7 antibody, ADRB2R antibody, ADRBR antibody, B2AR antibody, BAR antibody, BETA2AR antibody, adrenoceptor beta 2 antibody, adrenoceptor beta 2, surface b antibody, beta2-adrenergic receptor antibody, adrenergic receptor, beta 2 antibody, ADRB2 antibody, adrb2b antibody, LOC100136153 antibody, Adrb2 antibody
    背景
    This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ADRB2R, ADRBR, B2AR, BAR, BETA2AR
    Protein Interaction Partner: ARRDC3, REL, TSHR, TSG101, STAT4, STAT3, SNCG, RGS10, RGS2, RAN, RAB27A, RAB3A, CNN1, CD81, CD68, CD9, CD4, CCKBR, CEACAM1, ARRB2, ARHGDIA, ARHGAP5, HDAC6, GPR56, VAPA, RGS9, RGS11, RGS20, RGS5, VEGFB, VDAC2, VDAC1, KCTD13, ARRDC1, RGS8, SLC52A2, WNK1, RA
    Protein Size: 413
    分子量
    46 kDa
    基因ID
    154
    NCBI登录号
    NM_000024, NP_000015
    UniProt
    P07550
    途径
    cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
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