GCM2 抗体 (N-Term)
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北京 101111
Quick Overview for GCM2 抗体 (N-Term) (ABIN2792067)
抗原
See all GCM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- GCM2 Antibody - N-terminal region
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序列
- HSGYPVTNFW RLDGNAIFFQ AKGVHDHPRP ESKSETEARR SAIKRQMASF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against GCM2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human GCM2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72751-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GCM2 (Glial Cells Missing Homolog 2 (GCM2))
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别名
- GCM2
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背景
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Background Information: This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.
Alternative Symbols: FIH2, GCMB, HRPT4, hGCMb
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分子量
- 57kDa
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基因ID
- 9247
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NCBI登录号
- NP_004743
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UniProt
- O75603
抗原
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