TXN 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for TXN 抗体 (C-Term) (ABIN2792061)
抗原
See all TXN 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- TXN Antibody - C-terminal region
-
序列
- NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
-
产品特性
- This is a rabbit polyclonal antibody against TXN. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human TXN
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72618-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- TXN (Thioredoxin (TXN))
-
别名
- TXN
-
背景
-
Background Information: TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. It nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. It induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55)Alternative Symbols: TRX, TRDX, TRX1, Trx80
-
分子量
- 11kDa
-
基因ID
- 7295
-
NCBI登录号
- NP_003320
-
UniProt
- P10599
-
途径
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
抗原
-