Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeat freeze-thaw cycles.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原
TXN
(Thioredoxin (TXN))
别名
TXN
背景
TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. It nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. It induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55) Alias Symbols: TRDX, TRX, TRX1 Protein Interaction Partner: NR3C1, GPX1, APEX1, SRP9, PARK2, TXNIP, UBD, Melk, NPM1, PAN2, UBL4A, UBC, DYNLT1, SIAH1, NFE2, MYD88, MYC, MLH1, IFIT3, CDKN1A, ACTN4, GPRASP2, HCVgp1, PRDX1, MAP3K5, SFXN1, UBL5, UBQLN4, TAX1BP3, AHCYL1, SSSCA1, SYNCRIP, WDR1, ATP6V1F, UBE2V1, UBE2D2, S Protein Size: 105