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TXN 抗体 (C-Term)

This anti-TXN antibody is a 兔 多克隆 antibody detecting TXN in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Cow, Pig, 兔, 犬, 豚鼠, 马 和 绵羊.
产品编号 ABIN2792061
发货至: 中国

Quick Overview for TXN 抗体 (C-Term) (ABIN2792061)

抗原

See all TXN 抗体
TXN (Thioredoxin (TXN))

适用

人, 大鼠, 小鼠, Cow, Pig, 兔, 犬, 豚鼠, 马, 绵羊

宿主

  • 103
  • 48

克隆类型

  • 84
  • 67
多克隆

标记

  • 90
  • 19
  • 15
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
This TXN antibody is un-conjugated

应用范围

  • 114
  • 77
  • 63
  • 44
  • 36
  • 18
  • 16
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 39
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

    产品特性

    This is a rabbit polyclonal antibody against TXN. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human TXN
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    TXN (Thioredoxin (TXN))

    别名

    TXN

    背景

    TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. It nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. It induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
    ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55)
    Alias Symbols: TRDX, TRX, TRX1
    Protein Interaction Partner: NR3C1, GPX1, APEX1, SRP9, PARK2, TXNIP, UBD, Melk, NPM1, PAN2, UBL4A, UBC, DYNLT1, SIAH1, NFE2, MYD88, MYC, MLH1, IFIT3, CDKN1A, ACTN4, GPRASP2, HCVgp1, PRDX1, MAP3K5, SFXN1, UBL5, UBQLN4, TAX1BP3, AHCYL1, SSSCA1, SYNCRIP, WDR1, ATP6V1F, UBE2V1, UBE2D2, S
    Protein Size: 105

    分子量

    11 kDa

    基因ID

    7295

    NCBI登录号

    NM_003329, NP_003320

    UniProt

    P10599

    途径

    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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