BCR 抗体 (N-Term)
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北京 101111
Quick Overview for BCR 抗体 (N-Term) (ABIN2792051)
抗原
See all BCR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- BCR Antibody - N-terminal region
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序列
- EDFSSGQSSR VSPSPTTYRM FRDKSRSPSQ NSQQSFDSSS PPTPQCHKRH
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against BCR-ABL1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of human BCR
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anti-Breakpoint Cluster Region (BCR) (AA 139-280) antibody
BCR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E11G12 unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibodyBCR 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Breakpoint Cluster Region (BCR) antibodyKD Validated BCR 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB6945 unconjugated Recombinant Antibody
anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibodyBCR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-100) antibodyBCR 适用: 人, 小鼠, 大鼠 WB, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 50-100) antibodyBCR 适用: 人 ICC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (N-Term) antibodyBCR 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 50-100) antibodyBCR 适用: 人 WB, FACS, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1221-1271) antibodyBCR 适用: 人 WB, FACS, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibodyBCR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72510-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- BCR (Breakpoint Cluster Region (BCR))
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别名
- BCR
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背景
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Background Information: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: breakpoint cluster region
Alternative Symbols: ALL, CML, PHL, BCR1, D22S11, D22S662
Protein Name: breakpoint cluster region protein
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分子量
- 34kDa
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基因ID
- 613
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NCBI登录号
- NP_004318
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UniProt
- P11274
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途径
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
抗原
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