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PDZD3 抗体 (C-Term)

This anti-PDZD3 antibody is a 兔 多克隆 antibody detecting PDZD3 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, Pig 和 兔.
产品编号 ABIN2791850
发货至: 中国

Quick Overview for PDZD3 抗体 (C-Term) (ABIN2791850)

抗原

See all PDZD3 抗体
PDZD3 (PDZ Domain Containing 3 (PDZD3))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔

宿主

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克隆类型

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多克隆

标记

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This PDZD3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    APLAEGWALP TKPRCLHLEK GPQGFGFLLR EEKGLDGRPG QFLWEVDPGL

    预测反应

    Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against PDZD3. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDZD3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PDZD3 (PDZ Domain Containing 3 (PDZD3))

    别名

    PDZD3

    背景

    Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation.
    Protein Interaction Partner: SPRYD7, ASAP3, SLC41A3, CACNA1S, PTGIR, SLC22A4, SLCO1A2, SLC15A2, SLCO1C1, GUCY2C, SLCO3A1, SLC22A9, SLC22A3, SLC22A5, CFTR, ABCC2, SLC15A1,
    Protein Size: 571

    分子量

    62 kDa

    基因ID

    79849

    UniProt

    Q86UT5
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