NSMCE4A 抗体 (C-Term)
This anti-NSMCE4A antibody is a 兔 多克隆 antibody detecting NSMCE4A in WB 和 IF. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 和 斑马鱼.
Quick Overview for NSMCE4A 抗体 (C-Term) (ABIN2791705)
抗原
See all NSMCE4A 抗体
NSMCE4A
(Non-SMC Element 4 Homolog A (NSMCE4A))
适用
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
宿主
兔
克隆类型
多克隆
标记
This NSMCE4A antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF)
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抗原表位
- C-Term
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序列
- PVIQEERAMP AQLRRMEESH QEATEKEVER ILGLLQTYFR EDPDTPMSFF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against NSMCE4A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human NSMCE4A
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anti-Non-SMC Element 4 Homolog A (NSMCE4A) (C-Term) antibody
NSMCE4A 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Non-SMC Element 4 Homolog A (NSMCE4A) (AA 29-57), (N-Term) antibodyNSMCE4A 适用: 人 WB 宿主: 兔 Polyclonal RB24938 unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
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别名
- NSMCE4A
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背景
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NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
Alias Symbols: C10orf86, NS4EA, NSE4A
Protein Interaction Partner: UBC, HECW2, SRPK2, SRPK1, MAGED4B, NDNL2, MAGEC2, MAGEH1, MAGED2, NDN, MAGEB1, MAGEA1, NSMCE1, SMC6,
Protein Size: 385 -
分子量
- 44 kDa
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基因ID
- 54780
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NCBI登录号
- NM_017615, NP_060085
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UniProt
- Q9NXX6
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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