This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. Protein Interaction Partner: IFIT3, UBC, SUMO1, IFIT1B, DCD, TOE1, GRPEL1, MCCC2, MCCC1, PABPC1, IFIT5, IGF2BP1, PABPC4, SNRPF, SNRPE, SNRPD3, SNRPD2, SNRPD1, SNRPC, SNRPB2, SNRPB, SNRPA1, SNRPA, SNRNP70, S100A7, RPLP1, PCCB, PCCA, PC, YBX1, NCL, MOV10, ILF2, IFIT2, HSP90AB1, HSP90AA Protein Size: 447