MVB12B 抗体 (C-Term)
This anti-MVB12B antibody is a 兔 多克隆 antibody detecting MVB12B in WB. Suitable for 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马 和 兔.
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Quick Overview for MVB12B 抗体 (C-Term) (ABIN2791520)
抗原
See all MVB12B 抗体
MVB12B
(Multivesicular Body Subunit 12B (MVB12B))
适用
人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔
宿主
兔
克隆类型
多克隆
标记
This MVB12B antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- C-Term
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序列
- HISLTLPATF RGRNSTRTDY EYQHSNLYAI SAMDGVPFMI SEKFSCVPES
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against MVB12B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MVB12B
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MVB12B (Multivesicular Body Subunit 12B (MVB12B))
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别名
- MVB12B
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背景
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The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: C9orf28, MVB12B
Protein Interaction Partner: LNX1, gag, UBC, VPS37A, MVB12A, TSG101,
Protein Size: 319 -
分子量
- 35 kDa
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基因ID
- 89853
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NCBI登录号
- NM_033446, NP_258257
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UniProt
- Q9H7P6
抗原
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