DENND1C 抗体 (C-Term)
Quick Overview for DENND1C 抗体 (C-Term) (ABIN2790995)
抗原
See all DENND1C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PSSLEDPRAR PPKALLAERA HLQPREEPGA LNSPATPTSN CQKSQPSSRP
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against DENND1C. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND1C
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 801 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DENND1C (DENN/MADD Domain Containing 1C (DENND1C))
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别名
- DENND1C
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背景
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Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
Alias Symbols: FAM31C
Protein Interaction Partner: APP, ELAVL1,
Protein Size: 801 -
分子量
- 87 kDa
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基因ID
- 79958
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NCBI登录号
- NM_024898, NP_079174
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UniProt
- Q8IV53
抗原
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