YOD1 抗体 (N-Term)
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Quick Overview for YOD1 抗体 (N-Term) (ABIN2790891)
抗原
See all YOD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VPQSEAGTKA GPAGGRPADT MWRVRCKAKG GTHLLQGLSS RTRLRELQGQ
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against Yod1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Yod1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))
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别名
- Yod1
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背景
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Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Yod1 may act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Yod1 mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. It is able to cleave both polyubiquitin and di-ubiquitin.
Alias Symbols: 9930028C20Rik, Hshin7
Protein Size: 343 -
分子量
- 37 kDa
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基因ID
- 226418
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NCBI登录号
- NM_178691, NP_848806
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UniProt
- Q8CB27
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途径
- ER-Nucleus Signaling
抗原
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