MYSM1 抗体 (C-Term)
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- 抗原 See all MYSM1 抗体
- MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
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抗原表位
- C-Term
- 适用
- 人, 犬, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYSM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- CLQKLLECMR KTLSKVTNCF MAEEFLTEIE NLFLSNYKSN QENGVTEENC
- 预测反应
- Dog: 86%, Human: 100%, Rabbit: 77%
- 产品特性
- This is a rabbit polyclonal antibody against MYSM1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MYSM1
- Top Product
- Discover our top product MYSM1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 828 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
- 别名
- MYSM1 (MYSM1 产品)
- 背景
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MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. It preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Alias Symbols: 2A-DUB, 2ADUB, DKFZp779J1554, DKFZp779J1721, KIAA1915, RP4-592A1.1
Protein Interaction Partner: UBC, DICER1, SUMO2, TUBB1, WDR77, STK38, PRMT5, KAT2B, HIST2H2AC, RBM10, KIF11, HSPA1A, HNRNPH1, EEF1A1,
Protein Size: 828 - 分子量
- 91 kDa
- 基因ID
- 114803
- NCBI登录号
- NM_001085487, NP_001078956
- UniProt
- Q5VVJ2
- 途径
- Chromatin Binding
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