ATXN7L3 抗体 (Middle Region)
Quick Overview for ATXN7L3 抗体 (Middle Region) (ABIN2790607)
抗原
See all ATXN7L3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- MNKSESDQED NDDINDNDWS YGSEKKAKKR KSDKLWYLPF QNPNSPRRSK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against ATXN7L3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human ATXN7L3
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anti-Ataxin 7-Like 3 (ATXN7L3) antibody
ATXN7L3 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7-Like 3 (ATXN7L3) (Internal Region) antibodyATXN7L3 适用: 人, 小鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7-Like 3 (ATXN7L3) (AA 51-347) antibodyATXN7L3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7-Like 3 (ATXN7L3) (AA 126-175) antibodyATXN7L3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 354 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
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别名
- ATXN7L3
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背景
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ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Alias Symbols: DKFZp761G2113
Protein Interaction Partner: SIRT1, USP22, SECISBP2, SERTAD1, PICK1, USP6, UCHL3, HIST2H2BE, HIST2H2AC, ATXN7, KAT2A, ENY2, TAF5L, SUPT3H, TRRAP, TAF10,
Protein Size: 354 -
分子量
- 38 kDa
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基因ID
- 56970
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NCBI登录号
- NM_020218, NP_064603
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UniProt
- Q14CW9
抗原
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