ATF7IP2 抗体 (N-Term)
Quick Overview for ATF7IP2 抗体 (N-Term) (ABIN2790606)
抗原
See all ATF7IP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- EEIVHSETKL EQVVCSYQKP SRTTESPSRV FTEEAKDSLN TSENDSEHQT
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against ATF7IP2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ATF7IP2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 543 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))
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别名
- ATF7IP2
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背景
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ATF7IP2 is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. It can both act as an activator or a repressor depending on the context. ATF7IP2 mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity.
Alias Symbols: FLJ12668, MCAF2
Protein Interaction Partner: SETDB1, SP1, MBD1,
Protein Size: 543 -
分子量
- 59 kDa
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基因ID
- 80063
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NCBI登录号
- NM_001256160, NP_001243089
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UniProt
- Q5U623
抗原
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