IYD 抗体 (N-Term)
Quick Overview for IYD 抗体 (N-Term) (ABIN2790550)
抗原
See all IYD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- NADRSMEKKK GEPRTRAEAR PWVDEDLKDS SDLHQAEEDA DEWQESEENV
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预测反应
- Cow: 77%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against IYD. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human IYD
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anti-Iodotyrosine Deiodinase (IYD) (AA 24-147) antibody
IYD 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Iodotyrosine Deiodinase (IYD) (AA 22-71) antibodyIYD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Iodotyrosine Deiodinase (IYD) antibodyIYD 适用: 人 WB, ELISA, IHC 宿主: 兔 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 247 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IYD (Iodotyrosine Deiodinase (IYD))
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别名
- IYD
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背景
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This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4.
Alias Symbols: C6orf71, DEHAL1, TDH4, dJ422F24.1
Protein Interaction Partner: TRIM69,
Protein Size: 247 -
分子量
- 27 kDa
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基因ID
- 389434
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NCBI登录号
- NM_001164695, NP_001158167
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途径
- Thyroid Hormone Synthesis
抗原
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