DAND5 抗体 (C-Term)
Quick Overview for DAND5 抗体 (C-Term) (ABIN2790536)
抗原
See all DAND5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- YIPGSDPTPL VLCNSCMPAR KRWAPVVLWC LTGSSASRRR VKISTMLIEG
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against DAND5. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DAND5
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 189 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DAND5 (DAN Domain Family, Member 5 (DAND5))
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别名
- DAND5
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背景
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This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
Alias Symbols: CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, MGC126849, SP1
Protein Size: 189 -
分子量
- 21 kDa
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基因ID
- 199699
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NCBI登录号
- NM_152654, NP_689867
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UniProt
- Q8N907
抗原
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