D2HGDH 抗体 (C-Term)
Quick Overview for D2HGDH 抗体 (C-Term) (ABIN2790469)
抗原
See all D2HGDH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QESPFYVLIE TSGSNAGHDA EKLGHFLEHA LGSGLVTDGT MATDQRKVKM
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预测反应
- Dog: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 77%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against D2HGDH. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human D2HGDH
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 521 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))
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别名
- D2HGDH
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背景
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This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
Alias Symbols: D2HGD, FLJ42195, MGC25181
Protein Interaction Partner: SUMO1, UBC,
Protein Size: 521 -
分子量
- 55 kDa
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基因ID
- 728294
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NCBI登录号
- NM_152783, NP_689996
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UniProt
- Q8N465
抗原
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