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D2HGDH 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects D2HGDH in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 兔, 犬, 马 和 Pig.
产品编号 ABIN2790469
发货至: 中国
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Quick Overview for D2HGDH 抗体 (C-Term) (ABIN2790469)

抗原

See all D2HGDH 抗体
D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

适用

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人, 小鼠, 大鼠, 兔, 犬, 马, Pig

宿主

  • 19
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克隆类型

  • 19
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多克隆

标记

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This D2HGDH antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    QESPFYVLIE TSGSNAGHDA EKLGHFLEHA LGSGLVTDGT MATDQRKVKM

    预测反应

    Dog: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 77%, Rabbit: 100%, Rat: 92%

    产品特性

    This is a rabbit polyclonal antibody against D2HGDH. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human D2HGDH
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 521 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))

    别名

    D2HGDH

    背景

    This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.
    Alias Symbols: D2HGD, FLJ42195, MGC25181
    Protein Interaction Partner: SUMO1, UBC,
    Protein Size: 521

    分子量

    55 kDa

    基因ID

    728294

    NCBI登录号

    NM_152783, NP_689996

    UniProt

    Q8N465
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