SNX15 抗体 (N-Term)
Quick Overview for SNX15 抗体 (N-Term) (ABIN2790379)
抗原
See all SNX15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RKLHGDLAYT HRNLFRRLEE FPAFPRAQVF GRFEASVIEE RRKGAEDLLR
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SNX15. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SNX15
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 256 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SNX15 (Sorting Nexin 15 (SNX15))
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别名
- SNX15
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背景
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This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
Alias Symbols: HSAF001435
Protein Interaction Partner: REEP6, RTN4, ARL6IP1, RABAC1, KDM1A, FN1, METTL14, VPS36, SARAF,
Protein Size: 256 -
分子量
- 29 kDa
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基因ID
- 29907
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NCBI登录号
- NM_147777, NP_680086
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UniProt
- E5KQS6
抗原
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