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PIK3C2A 抗体 (C-Term)

PIK3C2A 适用: 人, 小鼠, 大鼠, 犬, Pig, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2790304
发货至: 中国
  • 抗原 See all PIK3C2A 抗体
    PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
    抗原表位
    • 9
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠, 犬, Pig, 马, 兔, 斑马鱼
    宿主
    • 38
    • 9
    • 1
    克隆类型
    • 40
    • 8
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIK3C2A antibody is un-conjugated
    应用范围
    • 39
    • 31
    • 21
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    PNPYVKTYLL PDNHKTSKRK TKISRKTRNP TFNEMLVYSG YSKETLRQRE
    预测反应
    Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against PIK3C2A. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of human PIK3C2A
    Top Product
    Discover our top product PIK3C2A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
    别名
    PIK3C2A (PIK3C2A 产品)
    别名
    CPK antibody, PI3-K-C2(ALPHA) antibody, PI3-K-C2A antibody, cpk antibody, pi3-k-c2a antibody, Cpk-m antibody, PI3KC2 antibody, sb:cb156 antibody, si:dkey-24l11.7 antibody, wu:fc02a04 antibody, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha antibody, phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha antibody, phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha S homeolog antibody, phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha antibody, PIK3C2A antibody, Pik3c2a antibody, pik3c2a antibody, pik3c2a.S antibody, LOC100548137 antibody
    背景
    The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
    Alias Symbols: CPK, PI3-K-C2A, PI3-K-C2(ALPHA)
    Protein Size: 1306
    分子量
    143 kDa
    基因ID
    5286
    NCBI登录号
    NM_002645, NP_002636
    UniProt
    O00443
    途径
    EGFR Signaling Pathway, Inositol Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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