Latrophilin 1 抗体 (C-Term)
Quick Overview for Latrophilin 1 抗体 (C-Term) (ABIN2790265)
抗原
See all Latrophilin 1 (LPHN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- YSLRSGDFPP GDGGPEPPRG RNLADAAAFE KMIISELVHN NLRGSSSAAK
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against LPHN1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human LPHN1
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anti-Latrophilin 1 (LPHN1) (C-Term) antibody
LPHN1 适用: 大鼠, 人, 小鼠, 猴, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Latrophilin 1 (LPHN1) (N-Term) antibodyLPHN1 适用: 大鼠, 人, 小鼠, Cow, 犬, 猴, Hamster, Bat, Pig, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Latrophilin 1 (LPHN1) (AA 480-494), (Extracellular) antibodyLPHN1 适用: 大鼠 WB, IF, IHC, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Latrophilin 1 (LPHN1) (AA 1-201) antibodyLPHN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Latrophilin 1 (LPHN1) (AA 1-201) antibodyLPHN1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4E12 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 839 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Latrophilin 1 (LPHN1)
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别名
- LPHN1
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背景
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This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane.
Alias Symbols: CIRL1, CL1, LEC2
Protein Interaction Partner: PSMA3, ELAVL1, UBC, CACNA1A, APC, ANKS1A, SHANK1, SHANK2, DLG4, DLG3, ROS1,
Protein Size: 839 -
分子量
- 95 kDa
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基因ID
- 22859
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NCBI登录号
- NM_001008701
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UniProt
- O94910
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途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
抗原
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