Importin 8 抗体 (C-Term)
Quick Overview for Importin 8 抗体 (C-Term) (ABIN2790260)
抗原
See all Importin 8 (IPO8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PPAVDAVVGQ IVPSILFLFL GLKQVCATRQ LVNREDRSKA EKADMEENEE
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预测反应
- Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against IPO8. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human IPO8
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 832 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Importin 8 (IPO8)
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别名
- IPO8
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背景
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The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ26580, RANBP8
Protein Interaction Partner: UBC, EGFR, YWHAE, CBX5, ATXN1, CUL3, Trim28, AGO4, AGO3, AGO2, AGO1, KPNB1, RANGAP1, SRP19, RPL23A,
Protein Size: 832 -
分子量
- 96 kDa
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基因ID
- 10526
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NCBI登录号
- NM_001190995, NP_001177924
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UniProt
- O15397
抗原
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