MOB1A 抗体 (C-Term)
Quick Overview for MOB1A 抗体 (C-Term) (ABIN2790218)
抗原
See all MOB1A (MOBKL1B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FDSVMQLQEE AHLNTSFKHF IFFVQEFNLI DRRELAPLQE LIEKLGSKDR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against MOB1A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MOB1A
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anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 2-216) antibody
MOBKL1B 适用: 人 ELISA, WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 1-216) antibodyMOBKL1B 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3E7B2 unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 1-216) antibodyMOBKL1B 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2D3D11 unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 188-216), (C-Term) antibodyMOBKL1B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19210 unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) antibodyMOBKL1B 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 167-216) antibodyMOBKL1B 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (Internal Region) antibodyMOBKL1B 适用: 人, 小鼠, 猴 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (Internal Region) antibodyMOBKL1B 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 5-33), (N-Term) antibodyMOBKL1B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19209 unconjugated
anti-MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B) (AA 4-33), (N-Term) antibodyMOBKL1B 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 216 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
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别名
- MOB1A
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背景
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MOB1A is an activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. MOB1A stimulates the kinase activity of STK38 and STK38L. MOB1A acts cooperatively with STK3/MST2 to activate STK38.
Alias Symbols: C2orf6, FLJ10788, FLJ11595, MATS1, MOB1, MOBK1B, Mob4B, MOBKL1B
Protein Interaction Partner: FAM9B, CMTM3, SEPT3, FAM118A, KANK2, TDO2, UBC, HECW2, ANKRD52, AMOT, ANKRD44, DOCK7, LRCH3, RASSF5, DOCK8, MOB2, SAV1, LRCH2, DOCK6, THOC2, PPP6R3, CRLF3, IPO11, LATS2, ANKRD28, LRCH1, STK38L, PPP6R1, RASSF2, PPP6R2, LATS1, YWHAH, STK4, STK3, PTPN14, PPP
Protein Size: 216 -
分子量
- 25 kDa
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基因ID
- 55233
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NCBI登录号
- NM_018221, NP_060691
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UniProt
- Q9H8S9
抗原
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