SELPLG 抗体 (C-Term)
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北京 101111
Quick Overview for SELPLG 抗体 (C-Term) (ABIN2790195)
抗原
See all SELPLG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- SELPLG Antibody - C-terminal region
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序列
- EMVCISSLLP DGGEGPSATA NGGLSKAKSP GLTPEPREDR EGDDLTLHSF
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预测反应
- Cow: 91%, Dog: 83%, Guinea Pig: 92%, Human: 100%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against SELPLG. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SELPLG
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65609-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SELPLG (Selectin P Ligand (SELPLG))
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别名
- SELPLG
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背景
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Background Information: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
Gene Name: Selectin P ligand
Alternative Symbols: CLA, CD162, PSGL1, PSGL-1
Protein Name: P-selectin glycoprotein ligand 1
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分子量
- 39kDa
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基因ID
- 6404
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NCBI登录号
- NP_002997
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UniProt
- Q14242
抗原
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