-
- 抗原 See all CCDC98 (FAM175A) 抗体
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
-
抗原表位
- C-Term
-
适用
- 人, 马, 兔, Cow, 犬, Pig
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CCDC98 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- DDRWQFKRSR LLDTQDKRSK ADTGSSNQDK ASKMSSPETD EEIEKMKGFG
- 预测反应
- Cow: 85%, Dog: 79%, Horse: 100%, Human: 100%, Pig: 79%, Rabbit: 100%
- 产品特性
- This is a rabbit polyclonal antibody against FAM175A. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product FAM175A Primary Antibody
-
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 51-150) antibody
FAM175A 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 1-313) antibodyFAM175A 适用: 人 WB, IP, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal ABRA1-01 unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 1-313) antibodyFAM175A 适用: 人 WB, IP, FACS 宿主: 小鼠 Monoclonal ABRA1-01 unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 350-400) antibodyFAM175A 适用: 人 WB, IP, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (N-Term) antibodyFAM175A 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 409 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
- 别名
- FAM175A (FAM175A 产品)
- 别名
- CCDC98 antibody, abra1 antibody, ccdc98 antibody, fam175a antibody, ABRA1 antibody, 3830405G04Rik antibody, 5630400M01Rik antibody, AI506069 antibody, AL024423 antibody, AV118690 antibody, Ccdc98 antibody, RGD1305287 antibody, zgc:103522 antibody, abraxas 1, BRCA1 A complex subunit antibody, Coiled-coil domain-containing protein 98 antibody, BRCA1 A complex subunit antibody, family with sequence similarity 175 member A antibody, abraxas 2a, BRISC complex subunit antibody, abraxas 1, BRCA1 A complex subunit S homeolog antibody, ABRAXAS1 antibody, abraxas1 antibody, Abraxas1 antibody, FAM175A antibody, abraxas2a antibody, abraxas1.S antibody
- 背景
-
FAM175A is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
Alias Symbols: ABRA1, CCDC98, FLJ11520, FLJ12642, FLJ13614
Protein Interaction Partner: FANCG, UIMC1, BRCA1, BRCC3, BABAM1, UBC, SUMO2, PAXIP1, MDC1, BARD1, BRE, HSPA4,
Protein Size: 409 - 分子量
- 47 kDa
- 基因ID
- 84142
- NCBI登录号
- NM_139076, NP_620775
- UniProt
- Q6UWZ7
- 途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
-
You are here:
