BRCA1-A Complex Subunit Abraxas 1 (ABRAXAS1) (C-Term) 抗体
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北京 101111
Quick Overview for BRCA1-A Complex Subunit Abraxas 1 (ABRAXAS1) (C-Term) 抗体 (ABIN2790106)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- ABRAXAS1 Antibody - C-terminal region
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序列
- DDRWQFKRSR LLDTQDKRSK ADTGSSNQDK ASKMSSPETD EEIEKMKGFG
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预测反应
- Cow: 85%, Dog: 79%, Horse: 100%, Human: 100%, Pig: 79%, Rabbit: 100%
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产品特性
- This is a rabbit polyclonal antibody against FAM175A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-BRCA1-A Complex Subunit Abraxas 1 (ABRAXAS1) antibody
ABRAXAS1 适用: 人 WB, IF, FACS, ICC, IP 宿主: 兔 Monoclonal 28A03 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65319-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- BRCA1-A Complex Subunit Abraxas 1 (ABRAXAS1)
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别名
- ABRAXAS1
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背景
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Targeted Subunit: Abraxas
Background Information: This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants.
Gene Name: abraxas 1, BRCA1 A complex subunit
Alternative Symbols: ABRA1, CCDC98, FAM175A
Protein Name: BRCA1-A complex subunit Abraxas 1
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分子量
- 47kDa
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基因ID
- 84142
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NCBI登录号
- NP_620775
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UniProt
- Q6UWZ7
抗原
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