TBXAS1 抗体 (C-Term)
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北京 101111
Quick Overview for TBXAS1 抗体 (C-Term) (ABIN2790095)
抗原
See all TBXAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- TBXAS1 Antibody - C-terminal region
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序列
- GYEIITNTLS FATYLLATNP DCQEKLLREV DVFKEKHMAP EFCSLEEGLP
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against TBXAS1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human TBXAS1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65284-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))
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别名
- TBXAS1
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背景
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Background Information: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: TS, TXS, CYP5, THAS, TXAS, CYP5A1, GHOSAL, BDPLT14
Protein Name: Thromboxane synthase EMBL AAA60617.1
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分子量
- 52kDa
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基因ID
- 6916
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NCBI登录号
- NP_112246
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UniProt
- Q16843
抗原
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