Myomesin 1 抗体 (C-Term)
Quick Overview for Myomesin 1 抗体 (C-Term) (ABIN2790069)
抗原
See all Myomesin 1 (MYOM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FEAGRTAYFT INGVSTADSG KYGLVVKNKY GSETSDFTVS VFIPEEEARM
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against MYOM1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Myomesin 1 (MYOM1) (AA 1586-1684) antibody
MYOM1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4F5 unconjugated
anti-Myomesin 1 (MYOM1) antibodyMYOM1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myomesin 1 (MYOM1) (AA 904-933) antibodyMYOM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32522 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1589 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Myomesin 1 (MYOM1)
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别名
- MYOM1
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背景
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The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50 % sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC134946, MGC134947, SKELEMIN
Protein Interaction Partner: TTN, MYH9, MYOM1,
Protein Size: 1589 -
分子量
- 178 kDa
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基因ID
- 8736
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NCBI登录号
- NM_019856, NP_062830
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UniProt
- P52179
抗原
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