IPO7 抗体 (C-Term)
Quick Overview for IPO7 抗体 (C-Term) (ABIN2789995)
抗原
See all IPO7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NVIQKMICEY SEEVTPIAVE MTQHLAMTFN QVIQTGPDEE GSDDKAVTAM
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against IPO7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1038 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IPO7 (Importin 7 (IPO7))
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别名
- IPO7
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背景
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The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions.
Alias Symbols: FLJ14581, Imp7, MGC138673, RANBP7
Protein Interaction Partner: SUMO2, SUMO3, STAU1, RNF2, rev, TNPO1, KARS, HSPA1L, HARS, APEH, PFDN5, NFRKB, ELAC2, CAND1, TRMT112, HSPA4L, RNASEH2A, FBXO6, EGFR, SOX2, METTL18, UBC, CFTR, CA9, IGBP1, RAN, CDK2, FBXO25, SIRT7, RNF146, MYC, AIRE, USP49, RPL23A, RPS7, RPL5, KPNB1, SRP19
Protein Size: 1038 -
分子量
- 119 kDa
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基因ID
- 10527
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NCBI登录号
- NM_006391, NP_006382
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UniProt
- O95373
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途径
- Protein targeting to Nucleus
抗原
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