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IPO7 抗体 (C-Term)

This anti-IPO7 antibody is a 兔 多克隆 antibody detecting IPO7 in WB. Suitable for 人, 小鼠, Cow, 大鼠, 犬, 马, 豚鼠, 兔, Pig 和 斑马鱼.
产品编号 ABIN2789995
发货至: 中国

Quick Overview for IPO7 抗体 (C-Term) (ABIN2789995)

抗原

See all IPO7 抗体
IPO7 (Importin 7 (IPO7))

适用

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人, 小鼠, Cow, 大鼠, 犬, 马, 豚鼠, 兔, Pig, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This IPO7 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    NVIQKMICEY SEEVTPIAVE MTQHLAMTFN QVIQTGPDEE GSDDKAVTAM

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against IPO7. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1038 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    IPO7 (Importin 7 (IPO7))

    别名

    IPO7

    背景

    The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions.
    Alias Symbols: FLJ14581, Imp7, MGC138673, RANBP7
    Protein Interaction Partner: SUMO2, SUMO3, STAU1, RNF2, rev, TNPO1, KARS, HSPA1L, HARS, APEH, PFDN5, NFRKB, ELAC2, CAND1, TRMT112, HSPA4L, RNASEH2A, FBXO6, EGFR, SOX2, METTL18, UBC, CFTR, CA9, IGBP1, RAN, CDK2, FBXO25, SIRT7, RNF146, MYC, AIRE, USP49, RPL23A, RPS7, RPL5, KPNB1, SRP19
    Protein Size: 1038

    分子量

    119 kDa

    基因ID

    10527

    NCBI登录号

    NM_006391, NP_006382

    UniProt

    O95373

    途径

    Protein targeting to Nucleus
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