EIF3I 抗体 (C-Term)
Quick Overview for EIF3I 抗体 (C-Term) (ABIN2789974)
抗原
See all EIF3I 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NVKEHSRQIN DIQLSRDMTM FVTASKDNTA KLFDSTTLEH QKTFRTERPV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against EIF3I. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 325 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
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别名
- EIF3I
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背景
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EIF3I is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Alias Symbols: EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36
Protein Interaction Partner: HUWE1, UBC, SUMO2, SUMO3, RNF2, rev, EIF3G, HECW2, EIF3B, CDK18, TARDBP, NPM1, ICAM1, CD81, IGSF8, PAN2, EIF3D, VCAM1, ITGA4, METTL18, gag-pol, DDX3X, PAXIP1, LIG4, EIF3L, EIF3K, EIF3M, EIF3H, EIF3F, EIF3C, EIF3A, EIF3E, CUL3, CDK2, YWHAZ, SIRT7, ARRB1, R
Protein Size: 325 -
分子量
- 36 kDa
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基因ID
- 8668
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NCBI登录号
- NM_003757, NP_003748
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UniProt
- Q13347
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA
抗原
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