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MMP25 抗体 (Middle Region)

MMP25 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789901
发货至: 中国
  • 抗原 See all MMP25 抗体
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    抗原表位
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马
    宿主
    • 31
    • 2
    克隆类型
    • 31
    • 2
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MMP25 antibody is un-conjugated
    应用范围
    • 18
    • 10
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    FGHALGLGHS SAPNSIMRPF YQGPVGDPDK YRLSQDDRDG LQQLYGKAPQ
    预测反应
    Dog: 82%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against MMP25. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product MMP25 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 562 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MMP25 (Matrix Metallopeptidase 25 (MMP25))
    别名
    MMP25 (MMP25 产品)
    别名
    MMP-25 antibody, MMP20 antibody, MMP20A antibody, MMPL1 antibody, MT-MMP 6 antibody, MT-MMP6 antibody, MT6-MMP antibody, MT6MMP antibody, MTMMP6 antibody, F730048C11Rik antibody, Leukolysin antibody, matrix metallopeptidase 25 antibody, MMP25 antibody, Mmp25 antibody
    背景
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
    Alias Symbols: MMP20, MMP20A, MMPL1, MT-MMP6, MT6-MMP
    Protein Interaction Partner: CLU, MMP2,
    Protein Size: 562
    分子量
    48 kDa
    基因ID
    64386
    NCBI登录号
    NM_022468, NP_071913
    UniProt
    Q9NPA2
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