CYFIP1 抗体 (C-Term)
Quick Overview for CYFIP1 抗体 (C-Term) (ABIN2789870)
抗原
See all CYFIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- WAGCMIIVLL GQQRRFAVLD FCYHLLKVQK HDGKDEIIKN VPLKKMVERI
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预测反应
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CYFIP1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYFIP1
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anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) (AA 320-449) antibody
CYFIP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) (AA 524-558) antibodyCYFIP1 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB47040 unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) (AA 1-270) antibodyCYFIP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1) antibodyKD Validated CYFIP1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, FACS 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1253 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
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别名
- CYFIP1
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背景
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CYFIP1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA By similarity. CYFIP1 regulates formation of membrane ruffles and lamellipodia. CYFIP1 plays a role in axon outgrowth. CYFIP1 binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. CYFIP1 may act as an invasion suppressor in cancers.
Alias Symbols: FLJ45151, P140SRA-1, SHYC, SRA1
Protein Interaction Partner: EFHC2, SUMO2, MEOX1, UBC, WWOX, PRPF40A, CLUH, TCERG1, NCKAP1, ARHGEF1, GAS7, APBB1, HECW2, RFX6, EFTUD2, SCTR, PPP1CC, GNB1, UBD, MARK4, YWHAZ, YWHAH, RYK, TERF2, TERF1, CYFIP1, RAC1, FMR1, ACTA1, FXR2, FXR1, NCL,
Protein Size: 1253 -
分子量
- 145 kDa
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基因ID
- 23191
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NCBI登录号
- NM_014608, NP_055423
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UniProt
- Q7L576
抗原
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