NCK1 抗体 (N-Term)
Quick Overview for NCK1 抗体 (N-Term) (ABIN2789859)
抗原
See all NCK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PSNYVERKNS ARKASIVKNL KDTLGIGKVK RKPSVPDSAS PADDSFVDPG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against NCK1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 377 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NCK1 (NCK Adaptor Protein 1 (NCK1))
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别名
- NCK1
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背景
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The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Alias Symbols: MGC12668, NCK, NCKalpha, nck-1
Protein Interaction Partner: UBC, CBL, SYNPO, WAS, Dok1, HSPA5, Mbp, SHANK3, KIAA1522, Caskin1, LPHN2, ADAM15, TUBA1A, ERBB3, EGFR, PHC2, FGFR1, MAP4K1, BCAR1, nef, ABI1, PAK1, DNM1, ABL1, TNK2, FASLG, UBASH3B, SYK, PIK3R1, LCP2, INPP5D, GRB2, KHDRBS1, UBA52, RASA1, NCKAP5, TNIK, BRK
Protein Size: 377 -
分子量
- 42 kDa
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基因ID
- 4690
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NCBI登录号
- NM_006153, NP_006144
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UniProt
- P16333
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途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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