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FLNC 抗体 (N-Term)

FLNC 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789843
发货至: 中国
  • 抗原 See all FLNC 抗体
    FLNC (Filamin C, gamma (FLNC))
    抗原表位
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 25
    • 24
    • 15
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼
    宿主
    • 28
    • 2
    克隆类型
    • 29
    • 1
    多克隆
    标记
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLNC antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    VGKSADFVVE AIGTEVGTLG FSIEGPSQAK IECDDKGDGS CDVRYWPTEP
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against FLNC. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human FLNC
    Top Product
    Discover our top product FLNC Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 2692 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Begay, Tharp, Martin, Graw, Sinagra, Miani, Sweet, Slavov, Stafford, Zeller, Alnefaie, Rowland, Brun, Jones, Gowan, Mestroni, Garrity, Taylor: "FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy." in: JACC. Basic to translational science, Vol. 1, Issue 5, pp. 344-359, (2016) (PubMed).

  • 抗原
    FLNC (Filamin C, gamma (FLNC))
    别名
    FLNC (FLNC 产品)
    别名
    1110055E19Rik antibody, ABP-280 antibody, ABPL antibody, Fln2 antibody, ABP280A antibody, ABPA antibody, FLN2 antibody, MFM5 antibody, MPD4 antibody, filamin C antibody, filamin C L homeolog antibody, filamin C, gamma antibody, FLNC antibody, flnc.L antibody, flnc antibody, Flnc antibody
    背景
    This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: ABP-280, ABP280A, ABPA, ABPL, FLJ10186, FLN2
    Protein Interaction Partner: RAPGEF2, TRIM63, TRIM55, XIRP1, XIRP2, SYNPO2, UBC, KCMF1, CTTNBP2NL, ANKRD28, ARFGEF2, NCAPD2, TXNL1, PSMD13, PSMD12, PSMD3, NUP88, IKBKB, FLNB, AP3S1, NPM1, IGSF8, FN1, IQCB1, TP63, VCAM1, RPS6KA2, DYNLRB1, NUP133, SAP30BP, SF3A3, SRSF9, ENO1, EEF1G, EE
    Protein Size: 2692
    分子量
    296 kDa
    基因ID
    2318
    NCBI登录号
    NM_001127487, NP_001120959
    UniProt
    Q14315
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