FLNC 抗体 (N-Term)
(1 reference)Quick Overview for FLNC 抗体 (N-Term) (ABIN2789843)
抗原
See all FLNC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VGKSADFVVE AIGTEVGTLG FSIEGPSQAK IECDDKGDGS CDVRYWPTEP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against FLNC. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human FLNC
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anti-Filamin C, gamma (FLNC) (AA 17-259) antibody
FLNC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Filamin C, gamma (FLNC) (AA 2606-2705) antibodyFLNC 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Filamin C, gamma (FLNC) (AA 2519-2725) antibodyFLNC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Filamin C, gamma (FLNC) antibodyFLNC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Filamin C, gamma (FLNC) antibodyFLNC 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin C, gamma (FLNC) (AA 2160-2340) antibodyFLNC 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Filamin C, gamma (FLNC) (AA 251-350) antibodyFLNC 适用: 小鼠, 大鼠, Chimpanzee WB, ICC, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 2692 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy." in: JACC. Basic to translational science, Vol. 1, Issue 5, pp. 344-359, (2016) (PubMed).
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: "FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy." in: JACC. Basic to translational science, Vol. 1, Issue 5, pp. 344-359, (2016) (PubMed).
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- FLNC (Filamin C, gamma (FLNC))
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别名
- FLNC
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背景
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This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ABP-280, ABP280A, ABPA, ABPL, FLJ10186, FLN2
Protein Interaction Partner: RAPGEF2, TRIM63, TRIM55, XIRP1, XIRP2, SYNPO2, UBC, KCMF1, CTTNBP2NL, ANKRD28, ARFGEF2, NCAPD2, TXNL1, PSMD13, PSMD12, PSMD3, NUP88, IKBKB, FLNB, AP3S1, NPM1, IGSF8, FN1, IQCB1, TP63, VCAM1, RPS6KA2, DYNLRB1, NUP133, SAP30BP, SF3A3, SRSF9, ENO1, EEF1G, EE
Protein Size: 2692 -
分子量
- 296 kDa
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基因ID
- 2318
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NCBI登录号
- NM_001127487, NP_001120959
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UniProt
- Q14315
抗原
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