AQR 抗体 (C-Term)
Quick Overview for AQR 抗体 (C-Term) (ABIN2789836)
抗原
See all AQR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- DTTPSETGAT STPEAIPALS ETTPTVVGAV SAPAEANTPQ DATSAPEETK
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预测反应
- Horse: 79%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against AQR. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human AQR
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1485 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AQR (Aquarius Homolog (AQR))
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别名
- AQR
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背景
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AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Alias Symbols: DKFZp686B23123, IBP160, KIAA0560, fSAP164
Protein Interaction Partner: UBC, LGR4, SUZ12, RNF2, BMI1, ZNF830, WDR83, WDR77, RBM22, PQBP1, RBM4, EIF4A3, MAGOH, SIRT7, HNRNPA1, Prpf8, Cdc5l, Snw1, USP28,
Protein Size: 1485 -
分子量
- 171 kDa
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基因ID
- 9716
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NCBI登录号
- NM_014691, NP_055506
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UniProt
- O60306
抗原
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